Sleeping Beauty transposon integrates into non-TA dinucleotides

Sleeping Beauty transposon integrates into non-TA dinucleotides

Abstract Background Sleeping Beauty transposon (SB) has become an increasingly important genetic tool for generating mutations in vertebrate cells. It is widely thought that SB exclusively integrates into TA dinucleotides. However, this strict TA-preference has not been rigorously tested in large nu...

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Bibliographic Details
Main Authors: Yabin Guo, Yin Zhang, Kaishun Hu
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Mobile DNA
Subjects:
Sleeping beauty
Transposon
Integration
Non-TA dinucleotide
Asymmetric
Non-palindromic
Online Access:http://link.springer.com/article/10.1186/s13100-018-0113-8

Internet

http://link.springer.com/article/10.1186/s13100-018-0113-8

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