Predicting transmembrane helix packing arrangements using residue contacts and a force-directed algorithm.
Alpha-helical transmembrane proteins constitute roughly 30% of a typical genome and are involved in a wide variety of important biological processes including cell signalling, transport of membrane-impermeable molecules and cell recognition. Despite significant efforts to predict transmembrane prote...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-03-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2841610?pdf=render |