Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy.

Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy.

The major obstacles to treatment of pancreatic cancer are the highly invasive capacity and resistance to chemo- and radiotherapy. Glycogen synthase kinase 3β (GSK3β) regulates multiple cellular pathways and is implicated in various diseases including cancer. Here we investigate a pathological role f...

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Bibliographic Details
Main Authors: Ayako Kitano, Takeo Shimasaki, Yuri Chikano, Mitsutoshi Nakada, Mayumi Hirose, Tomomi Higashi, Yasuhito Ishigaki, Yoshio Endo, Takahisa Takino, Hiroshi Sato, Yoshimichi Sai, Ken-Ichi Miyamoto, Yoshiharu Motoo, Kazuyuki Kawakami, Toshinari Minamoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3568118?pdf=render

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http://europepmc.org/articles/PMC3568118?pdf=render

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