Cancer-derived exosome miRNAs induce skeletal muscle wasting by Bcl-2-mediated apoptosis in colon cancer cachexia

Cancer cachexia is a kind of whole-body metabolic disorder syndrome accompanied by severe wasting of muscle tissue in which cancer exosomes may be involved. Analysis of clinical samples showed that the serum exosome concentrations were correlated with the development of cancer cachexia. Exosomes sec...

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Bibliographic Details
Main Authors: Chunxiao Miao, Wanli Zhang, Lixing Feng, Xiaofan Gu, Qiang Shen, Shanshan Lu, Meng Fan, Yiwei Li, Xianling Guo, Yushui Ma, Xuan Liu, Hui Wang, Xiongwen Zhang
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121001098