Effects of mesenchymal stromal cells on monocyte differentiation to M1 phenotype and M1/M2 macrophage switching

Effects of mesenchymal stromal cells on monocyte differentiation to M1 phenotype and M1/M2 macrophage switching

Objective. Mesenchymal stromal cells (MSCs) promote the differentiation of unprimed macrophages (Mр) or classically activated M1 cells towards alternatively activated, M2 macrophages. The aim of the work was to study the ability of MSC to induce M1→M2 switching by comparing the MSC effects on polari...

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Bibliographic Details
Main Authors: E. Ya. Shevela, L. V. Sakhno, M. A. Tikhonova, E. V. Batorov, A. A. Ostanin, E. R. Chernykh
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2018-03-01
Series:Bûlleten' Sibirskoj Mediciny
Subjects:
mesenchymal stromal cells, monocytes, macrophages, m1→m2 polarization, cytokines, chemokines
Online Access:https://bulletin.tomsk.ru/jour/article/view/1127

Internet

https://bulletin.tomsk.ru/jour/article/view/1127

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