In Vivo Estimation of Bioartificial Liver with Recombinant HepG2 Cells Using Pigs with Ischemic Liver Failure

Biological efficacy of a recombinant human hepatic cell line, glutamine synthetase transfected HepG2 (GS-HepG2), was examined with large-scale culture in a circulatory flow bioreactor and in pigs with ischemic liver failure. GS-HepG2 cells were cultured in a circulatory flow bioreactor from 5 × 107...

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Bibliographic Details
Main Authors: Shin Enosawa, Tomoyuki Miyashita, Yuji Fujita, Seiichi Suzuki, Hiroshi Amemiya, Takeshi Omasa, Shinya Hiramatsu, Kenichi Suga, Toshiharu Matsumura
Format: Article
Language:English
Published: SAGE Publishing 2001-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000001783986459