Combination of Vildagliptin and Ischemic Postconditioning in Diabetic Hearts as a Working Strategy to Reduce Myocardial Reperfusion Injury by Restoring Mitochondrial Function and Autophagic Activity

Combination of Vildagliptin and Ischemic Postconditioning in Diabetic Hearts as a Working Strategy to Reduce Myocardial Reperfusion Injury by Restoring Mitochondrial Function and Autophagic Activity

Purpose: Diabetic hearts are resistant to cardioprotection by ischemic-postconditioning (IPostC). Protection of diabetic hearts and finding related interfering mechanisms would have clinical benefits. This study investigated the combination effects of vildagliptin (Vilda) and IPostC on cardioprotect...

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Bibliographic Details
Main Authors: Goltaj Bayrami, Alireza Alihemmati, Pouran Karimi, Aniseh Javadi, Rana Keyhanmanesh, Mustafa Mohammadi, Milad Zadi-Heydarabad, Reza Badalzadeh
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-06-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Ischemic postconditioning
Diabetes
Reperfusion injury
Autophagy
Mitochondrial function
Online Access:http://apb.tbzmed.ac.ir/PDF/apb-8-319.pdf

Internet

http://apb.tbzmed.ac.ir/PDF/apb-8-319.pdf

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