Performance of the marginal structural cox model for estimating individual and joined effects of treatments given in combination

Performance of the marginal structural cox model for estimating individual and joined effects of treatments given in combination

Abstract Background The Marginal Structural Cox Model (Cox-MSM), an alternative approach to handle time-dependent confounder, was introduced for survival analysis and applied to estimate the joint causal effect of two time-dependent nonrandomized treatments on survival among HIV-positive subjects. N...

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Bibliographic Details
Main Authors: Clovis Lusivika-Nzinga, Hana Selinger-Leneman, Sophie Grabar, Dominique Costagliola, Fabrice Carrat
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Medical Research Methodology
Subjects:
Causal inference
Time-dependent confounding
Longitudinal data
Marginal structural models
Multitherapy
Online Access:http://link.springer.com/article/10.1186/s12874-017-0434-1

Internet

http://link.springer.com/article/10.1186/s12874-017-0434-1

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