Functional characteristics of CYP3A4 allelic variants on the metabolism of loperamide in vitro

Functional characteristics of CYP3A4 allelic variants on the metabolism of loperamide in vitro

Qian-Meng Lin,1 Ying-Hui Li,1 Qian Liu,1 Ni-Hong Pang,1 Ren-Ai Xu,2 Jian-Ping Cai,3 Guo-Xin Hu1 1School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, People’s Republic of China; 2Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University,...

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Bibliographic Details
Main Authors: Lin QM, Li YH, Liu Q, Pang NH, Xu RA, Cai JP, Hu GX
Format: Article
Language:English
Published: Dove Medical Press 2019-09-01
Series:Infection and Drug Resistance
Subjects:
CYP3A4
genetic polymorphism
interindividual variability
loperamide
misuse and abuse
cardiotoxicity
personalized treatment
Online Access:https://www.dovepress.com/functional-characteristics-of-cyp3a4-allelic-variants-on-the-metabolis-peer-reviewed-article-IDR

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https://www.dovepress.com/functional-characteristics-of-cyp3a4-allelic-variants-on-the-metabolis-peer-reviewed-article-IDR

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