Aging Kit mutant mice develop cardiomyopathy.

Both bone marrow (BM) and myocardium contain progenitor cells expressing the c-Kit tyrosine kinase. The aims of this study were to determine the effects of c-Kit mutations on: i. myocardial c-Kit(+) cells counts and ii. the stability of left ventricular (LV) contractile function and structure during...

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Bibliographic Details
Main Authors: Lei Ye, Eric Yang Zhang, Qiang Xiong, Clinton M Astle, Pengyuan Zhang, Qinglu Li, Arthur H L From, David E Harrison, Jianyi Jay Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3302804?pdf=render