Inhibitory Monoclonal Antibodies and Their Recombinant Derivatives Targeting Surface-Exposed Carbonic Anhydrase XII on Cancer Cells

Inhibitory Monoclonal Antibodies and Their Recombinant Derivatives Targeting Surface-Exposed Carbonic Anhydrase XII on Cancer Cells

Monoclonal and recombinant antibodies are widely used for the diagnostics and therapy of cancer. They are generated to interact with cell surface proteins which are usually involved in the development and progression of cancer. Carbonic anhydrase XII (CA XII) contributes to the survival of tumors un...

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Bibliographic Details
Main Authors: Dovile Stravinskiene, Aiste Sliziene, Lina Baranauskiene, Vilma Petrikaite, Aurelija Zvirbliene
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
carbonic anhydrase XII
cancer immunotherapy
monoclonal antibody
recombinant antibody
single-chain fragment variable
hybridoma
Online Access:https://www.mdpi.com/1422-0067/21/24/9411

Internet

https://www.mdpi.com/1422-0067/21/24/9411

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