Molecular modeling and design of some β-amino alcohol grafted 1,4,5-trisubstituted 1,2,3-triazoles derivatives against chloroquine sensitive, 3D7 strain of Plasmodium falciparum

Molecular modeling and design of some β-amino alcohol grafted 1,4,5-trisubstituted 1,2,3-triazoles derivatives against chloroquine sensitive, 3D7 strain of Plasmodium falciparum

Resistance nature of Plasmodium falciparum (P. falciparum) to the most effective antimalarial drug, Artemisinin, intimidate the global goal of total eradication of malarial. In an attempt to overcome this challenge, the research was aimed at designing derivatives of β-amino alcohol grafted 1,4,5-tri...

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Bibliographic Details
Main Authors: Zakari Ya'u Ibrahim, Adamu Uzairu, Gideon Adamu Shallangwa, Stephen Eyije Abechi
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Heliyon
Subjects:
Molecular modeling
Design
Antimalarial agent
β-Amino alcohol grafted 1,4,5-trisubstituted 1, 2, 3-triazoles
Molecular descriptors
First ionization potential
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021000293

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http://www.sciencedirect.com/science/article/pii/S2405844021000293

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