Foetal loss and enhanced fertility observed in mice treated with Zidovudine or Nevirapine.

Health concerns for HIV-infected persons on antiretroviral therapy (ART) have moved from morbidity to the challenges of long-term ART. We investigated the effect of Zidovudine or Nevirapine on reproductive capacity across two mouse generations.A prospective mouse study with drugs administered throug...

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Bibliographic Details
Main Authors: Chika K Onwuamah, Oliver C Ezechi, Ebiere C Herbertson, Rosemary A Audu, Innocent A O Ujah, Peter G C Odeigah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4169457?pdf=render