THAP1: Role in Mouse Embryonic Stem Cell Survival and Differentiation

THAP1: Role in Mouse Embryonic Stem Cell Survival and Differentiation

THAP1 (THAP [Thanatos-associated protein] domain-containing, apoptosis-associated protein 1) is a ubiquitously expressed member of a family of transcription factors with highly conserved DNA-binding and protein-interacting regions. Mutations in THAP1 cause dystonia, DYT6, a neurologic movement disor...

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Bibliographic Details
Main Authors: Francesca Aguilo, Zuchra Zakirova, Katie Nolan, Ryan Wagner, Rajal Sharma, Megan Hogan, Chengguo Wei, Yifei Sun, Martin J. Walsh, Kevin Kelley, Weijia Zhang, Laurie J. Ozelius, Pedro Gonzalez-Alegre, Thomas P. Zwaka, Michelle E. Ehrlich
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Stem Cell Reports
Subjects:
Thanatos-associated protein domain-containing apoptosis-associated protein 1
THAP1
dystonia
differentiation
survival
embryonic stem cells
transcriptomics
neuroectodermal differentiation
apoptosis
zinc finger transcription factor
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117301868

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http://www.sciencedirect.com/science/article/pii/S2213671117301868

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