Cigarette smoke extract upregulates heme oxygenase-1 via PKC/NADPH oxidase/ROS/PDGFR/PI3K/Akt pathway in mouse brain endothelial cells

<p>Abstract</p> <p>Background</p> <p>In the brain, the inducible form of heme oxygenase (HO-1) has been recently demonstrated to exacerbate early brain injury produced by intracerebral hemorrhagic stroke which incident rate has been correlated with cigarette smoking pre...

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Bibliographic Details
Main Authors: Kou Yu, Hsiao Li-Der, Cheng Shin-Ei, Shih Ruey-Horng, Yang Chuen-Mao
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/104