<i>LAG3</i> and Its Ligands Show Increased Expression in High-Risk Uveal Melanoma

<i>LAG3</i> and Its Ligands Show Increased Expression in High-Risk Uveal Melanoma

Uveal melanoma (UM) is a rare ocular malignancy which originates in the uveal tract, and often gives rise to metastases. Potential targets for immune checkpoint inhibition are lymphocyte-activation gene 3 (LAG3) and its ligands. We set out to analyse the distribution of these molecules in UM. The ex...

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Bibliographic Details
Main Authors: Zahra Souri, Annemijn P. A. Wierenga, Wilma G. M. Kroes, Pieter A. van der Velden, Robert M. Verdijk, Michael Eikmans, Gregorius P. M. Luyten, Martine J. Jager
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
uveal melanoma
inflammation
metastasis
immunotherapy
LAG3
Galectin-3
Online Access:https://www.mdpi.com/2072-6694/13/17/4445

Internet

https://www.mdpi.com/2072-6694/13/17/4445

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