Intrinsically Active and Pacemaker Neurons in Pluripotent Stem Cell-Derived Neuronal Populations

Intrinsically Active and Pacemaker Neurons in Pluripotent Stem Cell-Derived Neuronal Populations

Neurons generated from pluripotent stem cells (PSCs) self-organize into functional neuronal assemblies in vitro, generating synchronous network activities. Intriguingly, PSC-derived neuronal assemblies develop spontaneous activities that are independent of external stimulation, suggesting the presen...

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Bibliographic Details
Main Authors: Sebastian Illes, Martin Jakab, Felix Beyer, Renate Gelfert, Sébastien Couillard-Despres, Alfons Schnitzler, Markus Ritter, Ludwig Aigner
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221367111400023X

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http://www.sciencedirect.com/science/article/pii/S221367111400023X

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