Platelet-derived growth factor receptor-β, carrying the activating mutation D849N, accelerates the establishment of B16 melanoma

<p>Abstract</p> <p>Background</p> <p>Platelet-derived growth factor (PDGF)-BB and PDGF receptor (PDGFR)-β are mainly expressed in the developing vasculature, where PDGF-BB is produced by endothelial cells and PDGFR-β is expressed by mural cells, including pericytes. PDG...

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Bibliographic Details
Main Authors: Suzuki Shioto, Heldin Carl-Henrik, Heuchel Rainer
Format: Article
Language:English
Published: BMC 2007-12-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/7/224