Age- and Intravenous Methotrexate-Associated Leukoencephalopathy and Its Neurological Impact in Pediatric Patients with Lymphoblastic Leukemia

Age- and Intravenous Methotrexate-Associated Leukoencephalopathy and Its Neurological Impact in Pediatric Patients with Lymphoblastic Leukemia

Methotrexate (MTX) is associated with leukoencephalopathy (LE) in children treated for lymphoblastic leukemia/lymphoma (ALL/LBL). However, large-scale studies with systematic MR acquisition and quantitative volumetric lesion information remain limited. Hence, the prevalence of lesion burdens and the...

Full description

Bibliographic Details
Main Authors: Ilona Rijmenams, Daan Moechars, Anne Uyttebroeck, Ahmed Radwan, Jeroen Blommaert, Sabine Deprez, Stefan Sunaert, Heidi Segers, Céline R. Gillebert, Jurgen Lemiere, Charlotte Sleurs
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
childhood hematology
chemotherapy
neurotoxicity
leukoencephalopathy
risk classification
Online Access:https://www.mdpi.com/2072-6694/13/8/1939

Internet

https://www.mdpi.com/2072-6694/13/8/1939

Similar Items