Submacular integration of hESC-RPE monolayer xenografts in a surgical non-human primate model

Submacular integration of hESC-RPE monolayer xenografts in a surgical non-human primate model

Abstract Background Human pluripotent stem cells (hPSCs) provide a promising cell source for retinal cell replacement therapy but often lack standardized cell production and live-cell shipment logistics as well as rigorous analyses of surgical procedures for cell transplantation in the delicate macu...

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Main Authors: Zengping Liu, Tanja Ilmarinen, Gavin S. W. Tan, Heidi Hongisto, Edmund Y. M. Wong, Andrew S. H. Tsai, Sami Al-Nawaiseh, Graham E. Holder, Xinyi Su, Veluchamy Amutha Barathi, Heli Skottman, Boris V. Stanzel
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Stem Cell Research & Therapy
Subjects:
Retinal pigmented epithelium
Pluripotent stem cells
Cellular therapy
Cell transplantation
Non-human primate model
Online Access:https://doi.org/10.1186/s13287-021-02395-6

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