Emerging bioinformatics approaches for analysis of NGS-derived coding and non-coding RNAs in neurodegenerative diseases

Emerging bioinformatics approaches for analysis of NGS-derived coding and non-coding RNAs in neurodegenerative diseases

Neurodegenerative diseases such as late-onset Alzheimer’s disease (LOAD) involve a genetically complex and still obscure ensemble of causative and risk factors accompanied by complex feedback responses. The advent of ‘high-throughput’ transcriptome investigation technologies such as deep sequecing i...

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Bibliographic Details
Main Authors: Alessandro eGuffanti, Alon eSimchovitz, Hermona eSoreq
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Neurodegenerative Diseases
Next-generation sequencing
Bioinformatics & Computational Biology
biological networks
non coding RNA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00089/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00089/full

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