Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses

Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses

Hijacking host ubiquitin pathways is essential for the replication of diverse viruses. However, the role of deubiquitinating enzymes (DUBs) in the interplay between viruses and the host is poorly characterized. Here, we demonstrate that specific DUBs are potent inhibitors of viral proteins from HIVs...

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Bibliographic Details
Main Authors: Wenying Gao, Yajuan Rui, Guangquan Li, Chenyang Zhai, Jiaming Su, Han Liu, Wenwen Zheng, Baisong Zheng, Wenyan Zhang, Yongjun Yang, Shucheng Hua, Xiaofang Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
USP8
deubiquitinating enzymes
antiviral activity
viral proteins
ubiquitin ligase
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.740713/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.740713/full

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