Three-dimensional model of glioblastoma by co-culturing tumor stem cells with human brain organoids

Emerging three-dimensional (3D) cultures of glioblastoma are becoming powerful models to study glioblastoma stem cell behavior and the impact of cell–cell and cell–microenvironment interactions on tumor growth and invasion. Here we describe a method for culturing human glioblastoma stem cells (GSCs)...

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Bibliographic Details
Main Authors: Roberta Azzarelli, Michela Ori, Anna Philpott, Benjamin D. Simons
Format: Article
Language:English
Published: The Company of Biologists 2021-02-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/10/2/bio056416