Unfolded Protein Response Differentially Regulates TLR4-Induced Cytokine Expression in Distinct Macrophage Populations

Cellular stress responses are often engaged at sites of inflammation and can alter macrophage cytokine production. We now report that macrophages in distinct states of differentiation or in different temporal stages of inflammatory response exhibit differential sensitivity to cell stress mediated al...

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Bibliographic Details
Main Authors: Lei Zhang, Paul G. Pavicic, Shyamasree Datta, Qiaoling Song, Xiaohan Xu, Wei Wei, Fan Su, Patricia A. Rayman, Chenyang Zhao, Thomas Hamilton
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01390/full