Urokinase receptor regulates nerve regeneration through its interaction with α5β1-integrin

Urokinase receptor regulates nerve regeneration through its interaction with α5β1-integrin

Purpose: Urokinase receptor (uPAR) promotes extracellular matrix proteolysis, regulates adhesion and cell migration, transduces intracellular signals through interactions with the lateral partners. The expression of uPAR and urokinase (uPA) is significantly upregulated in peripheral nerves after inj...

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Bibliographic Details
Main Authors: P.S. Klimovich, E.V. Semina, M.N. Karagyaur, K.D. Rysenkova, V.Yu. Sysoeva, N.A. Mironov, G.D. Sagaradze, A.A. Az'muko, V.S. Popov, K.A. Rubina, V.A. Tkachuk
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Peripheral nerve regeneration
Urokinase
uPAR
Integrin
Neuritogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220301992

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http://www.sciencedirect.com/science/article/pii/S0753332220301992

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