Apolipoprotein E Expression by Neurons Surviving Excitotoxic Stress

In the adult brain, apolipoprotein E (apoE) mRNA is thought to be expressed by nonneuronal cells. Yet, when a brain damage has occurred, the protein is found in neurons. We have studied apoE expression following systemic kainic acid (KA), injected in rats to induce hippocampal neurodegeneration. We...

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Bibliographic Details
Main Authors: U. Boschert, E. Merlo-Pich, Guy Higgins, A.D. Roses, S. Catsicas
Format: Article
Language:English
Published: Elsevier 1999-12-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996199902516