Transient phenomena in gene expression after induction of transcription.

When transcription of a gene is induced by a stimulus, the number of its mRNA molecules changes with time. Here we discuss how this time evolution depends on the shape of the mRNA lifetime distribution. Analysis of the statistical properties of this change reveals transient effects on polysomes, rib...

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Bibliographic Details
Main Authors: Carlus Deneke, Sophia Rudorf, Angelo Valleriani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3339862?pdf=render