Early Developmental and Evolutionary Origins of Gene Body DNA Methylation Patterns in Mammalian Placentas.

Over the last 20-80 million years the mammalian placenta has taken on a variety of morphologies through both divergent and convergent evolution. Recently we have shown that the human placenta genome has a unique epigenetic pattern of large partially methylated domains (PMDs) and highly methylated do...

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Bibliographic Details
Main Authors: Diane I Schroeder, Kartika Jayashankar, Kory C Douglas, Twanda L Thirkill, Daniel York, Pete J Dickinson, Lawrence E Williams, Paul B Samollow, Pablo J Ross, Danika L Bannasch, Gordon C Douglas, Janine M LaSalle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4524645?pdf=render