The polymorphic variants DRD2 rs1800497 and ABCB1 3435C>T are associated with antipsychotic safety parameters in adolescents with an acute psychotic episode: the results of a pilot study

The polymorphic variants DRD2 rs1800497 and ABCB1 3435C>T are associated with antipsychotic safety parameters in adolescents with an acute psychotic episode: the results of a pilot study

Children and adolescents are more likely than adults to experience adverse side effects when taking antipsychotics. Pharmacogenetic testing allows one to more accurately choose the initial dose of a drug. The genes of pharmacokinetic factors have been shown to be of high prognostic value for the saf...

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Bibliographic Details
Main Authors: D. V. Ivashchenko, S. Z. Khoang, M. Kh. Tazagulova, B. V. Makhmudova, N. I. Buromskaya, P. V. Shimanov, R. V. Deitch, I. V. Dorina, M. I. Nastovich, K. A. Akmalova, A. A. Kachanova, E. A. Grishina, L. M. Savchenko, Yu. S. Shevchenko, D. A. Sychev
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2020-10-01
Series:Nevrologiâ, Nejropsihiatriâ, Psihosomatika
Subjects:
pharmacogenetics
antipsychotics
adolescents
acute psychotic episode
safety
efficacy
Online Access:https://nnp.ima-press.net/nnp/article/view/1324

Internet

https://nnp.ima-press.net/nnp/article/view/1324

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