Exosomal 2′,3′‐CNP from mesenchymal stem cells promotes hippocampus CA1 neurogenesis/neuritogenesis and contributes to rescue of cognition/learning deficiencies of damaged brain

Exosomal 2′,3′‐CNP from mesenchymal stem cells promotes hippocampus CA1 neurogenesis/neuritogenesis and contributes to rescue of cognition/learning deficiencies of damaged brain

Abstract Mesenchymal stem cells (MSCs) have been used in clinical studies to treat neurological diseases and damage. However, implanted MSCs do not achieve their regenerative effects by differentiating into and replacing neural cells. Instead, MSC secretome components mediate the regenerative effect...

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Bibliographic Details
Main Authors: Shih‐Yin Chen, Meng‐chieh Lin, Jia‐Shiuan Tsai, Pei‐Lin He, Wen‐Ting Luo, Ing‐Ming Chiu, Harvey R. Herschman, Hua‐Jung Li
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Stem Cells Translational Medicine
Subjects:
CNP
cognition and memory
exosome
mesenchymal stem cell
neuritogenesis
neurogenesis
Online Access:https://doi.org/10.1002/sctm.19-0174

Internet

https://doi.org/10.1002/sctm.19-0174

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