Regulation of SIRT1 in vascular smooth muscle cells from streptozotocin-diabetic rats.

Sirtuins enzymes are a conserved family of nicotinamide adenine dinucleotide (NAD)-dependent deacetylases and ADP-ribosyltransferases that mediate responses to oxidative stress, fasting and dietary restriction in mammals. Vascular smooth muscle cells (VSMCs) are involved in many mechanisms that regu...

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Bibliographic Details
Main Authors: Alice Toniolo, Erica Alessia Warden, Alberto Nassi, Andrea Cignarella, Chiara Bolego
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3667130?pdf=render