Adenomatous Polyposis Coli loss controls cell cycle regulators and response to paclitaxel in MDA-MB-157 metaplastic breast cancer cells.

Adenomatous Polyposis Coli loss controls cell cycle regulators and response to paclitaxel in MDA-MB-157 metaplastic breast cancer cells.

Show other versions (1)

Adenomatous Polyposis Coli (APC) is lost in approximately 70% of sporadic breast cancers, with an inclination towards triple negative breast cancer (TNBC). TNBC is treated with traditional chemotherapy, such as paclitaxel (PTX); however, tumors often develop drug resistance. We previously created AP...

Full description

Bibliographic Details
Main Authors: Emily M Astarita, Sara M Maloney, Camden A Hoover, Bronwyn J Berkeley, Monica K VanKlompenberg, T Murlidharan Nair, Jenifer R Prosperi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0255738

Internet

https://doi.org/10.1371/journal.pone.0255738

Similar Items