Quantification and Evaluations of Catechin Hydrate Polymeric Nanoparticles Used in Brain Targeting for the Treatment of Epilepsy

Quantification and Evaluations of Catechin Hydrate Polymeric Nanoparticles Used in Brain Targeting for the Treatment of Epilepsy

To formulate novel chitosan (CS)-coated−PLGA−nanoparticles (NPs) using a central composite design approach and use them in order to improve brain bioavailability for catechin hydrate (CH) through direct nose-to-central nervous system (CNS) delivery for the evaluation of a compara...

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Bibliographic Details
Main Authors: Niyaz Ahmad, Rizwan Ahmad, Ridha Abdullah Alrasheed, Hassan Mohammed Ali Almatar, Abdullah Sami Al-Ramadan, Mohd Amir, Md Sarafroz
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceutics
Subjects:
catechin hydrate
chitosan-coated–plga–nanoparticles
epilepsy
uhplc-ms/ms
brain bioavailability and pharmacokinetic
Online Access:https://www.mdpi.com/1999-4923/12/3/203

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https://www.mdpi.com/1999-4923/12/3/203

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