Very Elevated IgE, Atopy, and Severe Infection: A Genomics-Based Diagnostic Approach to a Spectrum of Diseases

Elevated IgE has been long recognized as an important clinical marker of atopy but can be seen in a myriad of conditions. The discovery of autosomal dominant STAT3 deficiency marked the first recognition of hyper-IgE syndrome (HIES) and the first primary immunodeficiency linked to elevated IgE. Sinc...

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Bibliographic Details
Main Authors: A. Chin, S. Balasubramanyam, C. M. Davis
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Case Reports in Immunology
Online Access:http://dx.doi.org/10.1155/2021/2767012