RBM38 plays a tumor-suppressor role via stabilizing the p53-mdm2 loop function in hepatocellular carcinoma

RBM38 plays a tumor-suppressor role via stabilizing the p53-mdm2 loop function in hepatocellular carcinoma

Abstract Background Misregulation of the p53-mdm2 loop function is a major mechanism to promote hepatocellular carcinoma (HCC). RBM38, a member of the RNA recognition motif (RRM) family of RNA binding proteins (RBPs), plays a fundamental role in the posttranscriptional control of gene expression and...

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Bibliographic Details
Main Authors: Jiazhou Ye, Rong Liang, Tao Bai, Yan Lin, Rongyun Mai, Meng Wei, Xinqin Ye, Lequn Li, Feixiang Wu
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
RBM38
HCC
P53-mdm2 function loop
Tumor suppressor
Online Access:http://link.springer.com/article/10.1186/s13046-018-0852-x

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http://link.springer.com/article/10.1186/s13046-018-0852-x

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