LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields

LTP and LTD are involved in shaping hippocampal place field representations. Here, the authors show that de novo pathway-specific hippocampal LTD changes dynamics and stability of newly formed place fields, regulating acquisition and maintenance of novel spatial information in adult rats.

Bibliographic Details
Main Authors: Donovan M. Ashby, Stan B. Floresco, Anthony G. Phillips, Alexander McGirr, Jeremy K. Seamans, Yu Tian Wang
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20317-7