Evaluation of the impact of single-nucleotide polymorphisms on treatment response, survival and toxicity with cytarabine and anthracyclines in patients with acute myeloid leukaemia: a systematic review protocol

Evaluation of the impact of single-nucleotide polymorphisms on treatment response, survival and toxicity with cytarabine and anthracyclines in patients with acute myeloid leukaemia: a systematic review protocol

Abstract Introduction Acute myeloid leukaemia is the most common type of acute leukaemia in the world. Thus, the study of genetic alterations, such as single-nucleotide polymorphisms (SNPs), has contributed to a better understanding of the mechanisms underlying leukaemogenesis, to improve the progno...

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Bibliographic Details
Main Authors: Taynah Cascaes Puty, Jonathan Souza Sarraf, Tabata Cristina Do Carmo Almeida, Valter Cordeiro Barbosa Filho, Luis Eduardo Werneck de Carvalho, Fernando Luiz Affonso Fonseca, Fernando Adami
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Systematic Reviews
Subjects:
SNP
Standard chemotherapy
Acute myeloid leukaemia
Survival
Toxicity
Online Access:http://link.springer.com/article/10.1186/s13643-019-1011-y

Internet

http://link.springer.com/article/10.1186/s13643-019-1011-y

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