Anillin regulates breast cancer cell migration, growth, and metastasis by non-canonical mechanisms involving control of cell stemness and differentiation

Anillin regulates breast cancer cell migration, growth, and metastasis by non-canonical mechanisms involving control of cell stemness and differentiation

Abstract Background Breast cancer metastasis is driven by a profound remodeling of the cytoskeleton that enables efficient cell migration and invasion. Anillin is a unique scaffolding protein regulating major cytoskeletal structures, such as actin filaments, microtubules, and septin polymers. It is...

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Bibliographic Details
Main Authors: Dongdong Wang, Nayden G. Naydenov, Mikhail G. Dozmorov, Jennifer E. Koblinski, Andrei I. Ivanov
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Breast Cancer Research
Subjects:
Actin cytoskeleton
Invasion
E-cadherin
Actin-binding proteins
Keratins
Stem cells
Online Access:https://doi.org/10.1186/s13058-019-1241-x

Internet

https://doi.org/10.1186/s13058-019-1241-x

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