Design of targeted B cell killing agents.

Design of targeted B cell killing agents.

B cells play an important role in the pathogenesis of both systemic and organ-specific autoimmune diseases. Autoreactive B cells not only produce autoantibodies, but also are capable to efficiently present specific autoantigens to T cells. Furthermore, B cells can secrete proinflammatory cytokines a...

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Bibliographic Details
Main Authors: Alexey V Stepanov, Alexey A Belogurov, Natalia A Ponomarenko, Oleg A Stremovskiy, Leonid V Kozlov, Anna M Bichucher, Sergey E Dmitriev, Ivan V Smirnov, Olga G Shamborant, Dmitry S Balabashin, Lidia P Sashchenko, Alexander G Tonevitsky, Alain Friboulet, Alexander G Gabibov, Sergey M Deyev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3108985?pdf=render

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http://europepmc.org/articles/PMC3108985?pdf=render

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