Rapid analysis of heterogeneously methylated DNA using digital methylation-sensitive high resolution melting: application to the <it>CDKN2B </it>(<it>p15</it>) gene

<p>Abstract</p> <p>Background</p> <p>Methylation-sensitive high resolution melting (MS-HRM) methodology is able to recognise heterogeneously methylated sequences by their characteristic melting profiles. To further analyse heterogeneously methylated sequences, we adopte...

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Bibliographic Details
Main Authors: Candiloro Ida LM, Mikeska Thomas, Hokland Peter, Dobrovic Alexander
Format: Article
Language:English
Published: BMC 2008-11-01
Series:Epigenetics & Chromatin
Online Access:http://www.epigeneticsandchromatin.com/content/1/1/7