Inhibitors of Mammalian Aquaporin Water Channels

Inhibitors of Mammalian Aquaporin Water Channels

Aquaporins (AQPs) are water channel proteins that are essential to life, being expressed in all kingdoms. In humans, there are 13 AQPs, at least one of which is found in every organ system. The structural biology of the AQP family is well-established and many functions for AQPs have been reported in...

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Bibliographic Details
Main Authors: Mohammed Abir-Awan, Philip Kitchen, Mootaz M. Salman, Matthew T. Conner, Alex C. Conner, Roslyn M. Bill
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
aquaporin
AQP inhibitors
AQP modulators
functional assays
AQP expression
AQPs in disease
AQP structure
TGN-020
heavy metals
small molecule inhibitors
Online Access:https://www.mdpi.com/1422-0067/20/7/1589

Internet

https://www.mdpi.com/1422-0067/20/7/1589

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