Adrenergic alpha-1 pathway is associated with hypertension among Nigerians in a pathway-focused analysis.

The pathway-focused association approach offers a hypothesis driven alternative to the agnostic genome-wide association study. Here we apply the pathway-focused approach to an association study of hypertension, systolic blood pressure (SBP), and diastolic blood pressure (DBP) in 1614 Nigerians with...

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Bibliographic Details
Main Authors: Nicholas P Reder, Bamidele O Tayo, Babatunde Salako, Adesola Ogunniyi, Adebowale Adeyemo, Charles Rotimi, Richard S Cooper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3353888?pdf=render