Nurr1 promotes lung cancer apoptosis via enhancing mitochondrial stress and p53-Drp1 pathway

Mitochondrial homeostasis is vital for the progression of lung cancer. Nurr1 has been identified as a novel mediator of mitochondrial homeostasis in several types of cancers. The aim of our study was to investigate whether Nurr1 modulates the viability of A549 lung cancer cells by inducing mitochond...

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Bibliographic Details
Main Authors: Zhao Shu, Li Peng, Wang Peng, Yang Jing, Song Peng, Zhang Dong, Zhou Gang
Format: Article
Language:English
Published: De Gruyter 2019-07-01
Series:Open Life Sciences
Subjects:
p53
Online Access:https://doi.org/10.1515/biol-2019-0030