Well-posedness of a coupled PDE–ODE model of stem cell lineage involving homeostatic regulation

We present existence and uniqueness results for a proposed coupled nonlinear PDE–ODE model representing cancer population dynamics. We establish this global result using Banach fixed point theory. The model describes the evolution of two progenies of stem cell lineage consisting of healthy and mutat...

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Bibliographic Details
Main Authors: Iqra Batool, Naim Bajcinca
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Results in Applied Mathematics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590037420300455