Dnd1-mediated epigenetic control of teratoma formation in mouse

Spontaneous testicular teratoma develops from primordial germ cells (PGCs) in embryos; however, the molecular mechanisms underlying teratoma formation are not fully understood. Mutation of the dead-end 1 (Dnd1) gene, which encodes an RNA-binding protein, drastically enhances teratoma formation in th...

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Bibliographic Details
Main Authors: Wei Gu, Kentaro Mochizuki, Kei Otsuka, Ryohei Hamada, Asuka Takehara, Yasuhisa Matsui
Format: Article
Language:English
Published: The Company of Biologists 2018-01-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/7/1/bio032318