FAM168A participates in the development of chronic myeloid leukemia via BCR-ABL1/AKT1/NFκB pathway

FAM168A participates in the development of chronic myeloid leukemia via BCR-ABL1/AKT1/NFκB pathway

Abstract Background Although the prognosis of chronic myeloid leukemia (CML) has dramatically improved, the pathogenesis of CML remains elusive. Studies have shown that sustained phosphorylation of AKT1 plays a crucial role in the proliferation of CML cells. Evidence indicates that in tongue cancer...

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Bibliographic Details
Main Authors: Xiaorong Liu, Huirong Mai, Hanfang Jiang, Zhihao Xing, Dong Peng, Yuan Kong, Chunqing Zhu, Yunsheng Chen
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Cancer
Subjects:
Chronic myeloid leukemia
FAM168A
Cell proliferation
AKT1
BCR-ABL1
Online Access:http://link.springer.com/article/10.1186/s12885-019-5898-4

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http://link.springer.com/article/10.1186/s12885-019-5898-4

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