Locus coeruleus MRI contrast is reduced in Alzheimer's disease dementia and correlates with CSF Aβ levels

Locus coeruleus MRI contrast is reduced in Alzheimer's disease dementia and correlates with CSF Aβ levels

Abstract Introduction This study aimed to assess how interindividual differences in locus coeruleus (LC) magnetic resonance imaging (MRI) contrast relate to cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD). Methods LC MRI contrast was quantified in 73 individuals from the DZNE L...

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Bibliographic Details
Main Authors: Matthew J. Betts, Arturo Cardenas‐Blanco, Martin Kanowski, Annika Spottke, Stefan J. Teipel, Ingo Kilimann, Frank Jessen, Emrah Düzel
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Alzheimer's disease (AD)
Locus coeruleus (LC)
Cerebrospinal fluid (CSF)
Amyloid
Tau
Magnetic resonance imaging (MRI)
Online Access:https://doi.org/10.1016/j.dadm.2019.02.001

Internet

https://doi.org/10.1016/j.dadm.2019.02.001

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