Construction and high cytoplasmic expression of a tumoricidal single-chain antibody against hepatocellular carcinoma

Construction and high cytoplasmic expression of a tumoricidal single-chain antibody against hepatocellular carcinoma

<p>Abstract</p> <p>Background</p> <p>Hep27 monoclonal (Hep27 Mab) is an antibody against hepatocellular carcinoma. Hep27 Mab itself can inhibit the growth of a hepatocellular carcinoma cell line (HCC-S102). We attempted to produce a single-chain fragment (scFv), a small...

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Bibliographic Details
Main Authors: Imanaka Tadayuki, Tsukio Manae, Tungpradabkul Sumalee, Sandee Duanpen, Takagi Masahiro
Format: Article
Language:English
Published: BMC 2002-09-01
Series:BMC Biotechnology
Subjects:
Single-chain Fv (scFv)
Hepatocellular carcinoma (HCC)
Bacterial expression
Inclusion body
Online Access:http://www.biomedcentral.com/1472-6750/2/16

Internet

http://www.biomedcentral.com/1472-6750/2/16

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