ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies

The development of the B-lymphoid cell lineage is tightly controlled by the concerted action of a network of transcriptional and epigenetic regulators. EBF1, a central component of this network, is essential for B-lymphoid specification and commitment as well as for the maintenance of the B-cell ide...

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Bibliographic Details
Main Authors: Maria Mesuraca, Emanuela Chiarella, Stefania Scicchitano, Bruna Codispoti, Marco Giordano, Giovanna Nappo, Heather M. Bond, Giovanni Morrone
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/165238