TRIM47 promotes malignant progression of renal cell carcinoma by degrading P53 through ubiquitination

TRIM47 promotes malignant progression of renal cell carcinoma by degrading P53 through ubiquitination

Abstract Background Renal cell carcinoma (RCC) is one of the most common malignant tumors originating from the renal parenchymal urinary epithelial system. Tripartite motif 47 (TRIM47) is a member of the TRIM family proteins, which has E3 ligase activity and has been demonstrated to be involved in t...

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Bibliographic Details
Main Authors: Jia-xin Chen, Da Xu, Jian-wei Cao, Li Zuo, Zhi-tao Han, Yi-jun Tian, Chuan-min Chu, Wang Zhou, Xiu-wu Pan, Xin-gang Cui
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Cancer Cell International
Subjects:
Renal cell carcinoma
E3 ubiquitin ligase
Proliferation
P53
TRIM47
Online Access:https://doi.org/10.1186/s12935-021-01831-0

Internet

https://doi.org/10.1186/s12935-021-01831-0

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